Institut für Systembiotechnologie
Publikationen
-
Seo K, Shu W, Rückert-Reed C, Gerlinger P, Erb T, Kalinowski J, Wittmann C (2023)
From waste to health-supporting molecules: biosynthesis of natural products from lignin-, plastic- and seaweed-based monomers using metabolically engineered Streptomyces lividans.
Microb. Cell Fact. 22:262. PUBMED.
-
Stegmüller J, Rodríguez Estévez M, Shu W, Gläser L, Myronovskyi M, Rückert-Reed C, Kalinowski J, Luzhetskyy A, Wittmann C (2023)
Systems Metabolic Engineering of Streptomyces albidoflavus at the level of primary and secondary metabolism enhances production of the reverse anitbiotic nybomycin against multi-resistant Staphylococcus aureus.
Metab. Eng. 81:123-143. PUBMED.
-
Pause L, Weimer A, Wirth NT, Nguyen AV, Lenz C, Kohlstedt M, Wittmann C, Nikel PI, Lai B, Krömer JO (2023)
Anaerobic glucose uptake in Pseudomonas putida KT2440 in a bioelectrochemical system.
Microb. Biotechnol. In press. PUBMED.
-
Beganovic S, Rückert-Reed C, Sucipto H, Shu W, Gläser L, Patschkowski T, Struck B, Kalinowski J, Luzhetskyy A, Wittmann C (2023)
Systems biology of industrial oxytetracycline production in Streptomyces rimosus: the secrets of a mutagenized hyperproducer.
Microb. Cell Fact. 22:222. PUBMED.
-
Dietrich DL, Jovanovic S, Cao P, Kohlstedt M, Wittmann C (2023)
Refactoring the genetic architecture of a myxobacterial polyketide gene cluster enables enhanced heterologous docosahexaenoic acid production in Yarrowia lipolytica.
Microb. Cell Fact. 22:199. PUBMED.
-
Jovanovic S, Dietrich DL, Cao P, Kohlstedt M, Wittmann C (2023)
Multi-omics view of recombinant Yarrowia lipolytica: Enhanced ketogenic amino acid catabolism increases polyketide-synthase-driven docosahexaenoic production to high selectivity at the gram scale.
Metab. Eng. 80:45-65. PUBMED.
-
Tangyu M, Fritz M, Tan JP, Ye L, Bolten CJ, Bogicevic B, Wittmann C (2023)
Flavour by design: Food-grade lactic acid bacteria improve the volatile aroma spectrum of oat milk, sunflower seed milk, pea milk, and faba milk towards improved flavour and sensory perception.
Microb. Cell Fact. 22:133. PUBMED.
-
Pauli S, Lamber J, Kohlstedt M, Becker J, Wittmann C (2023)
Systems metabolic engineering upgrades Corynebacterium glutamicum to high-level production of the chiral drug precursor and cell-protective extremolyte L-pipecolic acid.
Metab. Eng. 77:100-117. PUBMED.
-
Christmann J, Cao P, Desiderato CK, Goldbeck O, Kohlstedt M, Becker J, Riedel CU, Wittmann C (2023)
High-efficiency production of the antimicrobial peptide pediocin PA-1 in metabolically engineered C. glutamicum using a microaerobic process at acidic pH and elevated levels of bivalent calcium ions
Microb. Cell Fact. 22:41. PUBMED.
-
Weiland F, Barton N, Kohlstedt M, Becker J, Wittmann C (2023)
Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics.
Metab. Eng. 75:153-169. PUBMED.
2024 Institut für Systembiotechnologie